Ireland
--:--IST
Recruiting Observational

Whole Exome Sequencing of Familial and Pediatric Forms of Vasculitis

NCT04006535 · tracked via the Priya Life Science France tracker
Sponsor
Benjamin Terrier
Phase
Observational
Started
2019-06-01
Last updated
2019-07-08

Condition(s) studied

Vasculitis

Investigational drug(s) / intervention(s)

genetic analysis

genetic analysis: Saliva sample collection for genetic analysis

Study summary

The FAMILYVASC study is a prospective observational study which will aim to identify susceptibility loci and genes for systemic vasculitis risk in patients with familial or pediatric forms of vasculitis. Genetic analysis based on whole exome sequencing will be carried out through salivary DNA.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
Accepted
Inclusion criteria for subjects with vasculitis * Children and adults * Patients with vasculitis, as defined in the Chapel Hill International Classification in its revised version of 2012 * Patient information and signed informed consent * Pregnant and breastfeeding women can be included in the study Inclusion criteria for healthy subjects * Children and adults * Do not have vasculitis, as defined in the Chapel Hill International Classification in its revised version of 2012, or relatives on the 1st; 2nd; 3rd or 4th degree of a patient with vasculitis * Patient information and signed informed consent * Pregnant and breastfeeding women can be included in the study Exclusion criteria: * Refusal of consent or inability to obtain consent * Dementia or unauthorized patient, for psychiatric or intellectual failure reasons, to receive information about the protocol and to give informed consent. * Uncooperative patient, or any pathology that could make the patient potentially non-compliant to the study procedures, and patients interned for regulatory or legal reasons.

Primary outcome measure(s)

  • Identification of susceptibility loci and genes — At the moment of enrollment

Trial sites (1)

FacilityCityRegionStatus
Hôpital Cochin - Department of Internal Medicine Paris Île-de-France Region Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04006535 on ClinicalTrials.gov ↗ ← All trials in France