French National Observatory on Infective Endocarditis

NCT03272724 · tracked via the Priya Life Science France tracker

Sponsor

Central Hospital, Nancy, France

Phase

Observational

Started

1991-01-01

Last updated

2025-09-23

Condition(s) studied

Infective Endocarditis

Study summary

The objective of this observatory is to provide a national database of infective endocarditis, informed by all volunteer centers, using a standardized case report forms.

Such an observatory will describe the clinical profile, microbiological, therapeutic and evolving of infective endocarditis (IE); analyze the risk factors for the disease and its prognosis factors of evolution; describe management practices; evaluate and compare in the real drug treatment strategies (including antibiotics) and surgical.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Major Patient * Supported in one of the participating centers * The application of diagnostic classification criteria of Duke modified by Li is carried out after collection of all the data at the end of the patient's hospitalization. Only patients meeting criteria for definite or possible endocarditis will be included in the analyses. * Registered with the French social security system Exclusion Criteria: • Refusal of the patient to participate.

Primary outcome measure(s)

history of heart disease — inclusion
status of heart valves, pre-existing heart conditions
risk factors, medical history — inclusion
associated diseases
origin of infection — period of 3 months before infective endocarditis
high risk procedures
weight — inclusion
kg
height — inclusion
cm
clinical symptoms — inclusion
cardiac, peripheral and neurological symptoms
biological outcomes — inclusion
blood count
microbiological outcomes — inclusion
identification of infecting organisms
diagnostic imaging — inclusion
description of tyhe imaging tests performed
antibiotic therapy — from inclusion to recovery
antibiotic treatment: type and duration
surgical procedures — from inclusion to recovery
description of surgical procedures

Trial sites (1)

Facility	City	Region	Status
CHRU	Vandœuvre-lès-Nancy	France	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03272724 on ClinicalTrials.gov ↗ ← All trials in France