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Clinical Trials in the EU / 2025-524345-28-00
Authorised, not yet recruiting Phase II

A Phase II, single-arm trial on the addition of the DLL3xCD3 bispecific T-cell engager obrixtamig (BI 764532) to standard-of-care platinum-based first-line treatment of advanced large-cell neuroendocrine carcinoma of the lung (ALPINE 2)

2025-524345-28-00 · tracked via the Priya Life Science EU tracker
Sponsor
Technische Universitaet Dresden
Sponsor type
Educational Institution
Therapeutic area
Neoplasms
Decision date
31/08/2026
Enrollment target
75
Sites
Germany

Condition studied

Male and female adult patients with locally advanced or metastatic large-cell neuroendocrine carcinoma of the lung not eligible for curative treatment

Investigational medicinal product(s)

BI 764532

Every trial of Obrixtamig across our registers →

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

overall survival

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-524345-28-00 on CTIS ↗ ← All trials in the EU