Tibialis Posterior Muscle Morphology in Flexible Flatfeet Subjects

NCT07854535 · tracked via the Priya Life Science Egypt tracker

Sponsor

Cairo University

Phase

Observational

Started

2026-10

Last updated

2026-10-02

Condition(s) studied

Flexible Flatfoot

Investigational drug(s) / intervention(s)

Tibialis Posterior Muscle Morphology Assessment

Tibialis Posterior Muscle Morphology Assessment: Assessment of tibialis posterior muscle morphology using B-mode diagnostic ultrasound as a non-invasive measurement method. The assessment is performed for research purposes and does not involve administration of treatment or modification of participants' usual care.

Study summary

The goal of this observational study is to assess tibialis posterior muscle morphology in adults with flexible flatfeet. The main question it aims to answer is:

Are there differences in tibialis posterior muscle morphology between adults with symptomatic flexible flatfeet, asymptomatic flexible flatfeet, and individuals with normal foot posture?

Participants will undergo clinical assessment of foot posture and symptoms and an ultrasound assessment of the tibialis posterior muscle. The study will compare muscle thickness, cross-sectional area, and echo intensity among the three groups.

Eligibility

Sex

ALL

Min age

18 Years

Max age

40 Years

Healthy volunteers

Accepted

Inclusion Criteria: * Adults aged 18 to 40 years. * Both males and females will be eligible to participate. * Body mass index (BMI) ≤30 kg/m². * Participants with flexible flatfoot will demonstrate a visible medial longitudinal arch in the non-weight-bearing position and flattening of the arch during full weight-bearing. * Participants with flexible flatfoot will have a Foot Posture Index-6 (FPI-6) score of ≥+6. * Participants in the normal foot posture control group will have an FPI-6 score ranging from 0 to +5. * Participants must be able to stand and walk independently without an assistive device. * Participants must be willing to participate in the study and provide informed consent. Exclusion Criteria: * History of previous surgery involving the foot, ankle, or lower limb. * History of significant trauma or fracture involving the foot, ankle, or lower limb. * Presence of rigid flatfoot or other structural foot deformities. * Presence of neurological disorders affecting the lower limb. * Presence of neuromuscular disorders affecting the lower limb. * Presence of systemic or inflammatory musculoskeletal conditions affecting the lower limb. * Current lower-limb injury or condition that may affect standing, walking, foot posture, or tibialis posterior muscle morphology. * Pregnancy. * Participants who are unable to follow the assessment procedures or complete the required study measurements.

Primary outcome measure(s)

Tibialis Posterior Muscle Thickness — Baseline assessment during a single study visit.
Tibialis posterior muscle thickness will be assessed using B-mode diagnostic ultrasonography with a high-frequency linear transducer. The ultrasound measurement site will be standardized at 30% of the shank length according to the predefined study protocol. Minimal transducer pressure will be applied to avoid muscle compression. Multiple images will be obtained, and the mean measurement will be used for statistical analysis.
Tibialis Posterior Muscle Cross-sectional Area — Baseline assessment during a single study visit.
Tibialis posterior muscle cross-sectional area will be assessed using B-mode diagnostic ultrasonography with a high-frequency linear transducer. The ultrasound measurement site will be standardized at 30% of the shank length according to the predefined study protocol. Minimal transducer pressure will be applied to avoid muscle compression. Multiple images will be obtained, and the mean cross-sectional area measurement will be used for statistical analysis.

Trial sites (1)

Facility	City	Region	Status
Faculty of Physical Therapy, Cairo University Cairo, Egypt	Cairo	Egypt

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07854535 on ClinicalTrials.gov ↗ ← All trials in Egypt