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Clinical Trials in Egypt / NCT07848165
Recruiting Not applicable

Probiotic Role in Prevention of Ventilator Associated Pneumonia in Critically- Ill Children Admitted at Pediatric Intensive Care Unit

NCT07848165 · tracked via the Priya Life Science Egypt tracker
Sponsor
Tanta University
Phase
Not applicable
Started
2026-07-01
Last updated
2026-09-29

Condition(s) studied

ProbioticVentilator Associated PneumoniaCritically- Ill Children

Investigational drug(s) / intervention(s)

ProbioticsStandard management

Probiotics: Critically ill ventilated children will receive standard management plus probiotics.

Standard management: Critically ill ventilated children will receive standard management only.

Study summary

The aim of the work is to evaluate the impact of Probiotics supplementation on prevention of ventilator associated pneumonia in critically ill children admitted at Pediatric Intensive Care Unit at Tanta University Hospitals.

Eligibility

Sex
ALL
Min age
1 Month
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: * Critically ill children from 1 month to 18 years. * Both sexes. * Ventilated not due to chest infection. Exclusion Criteria: * Children recently received enteral vaccines. * Children receiving chronic immunosuppressive such as chemotherapy agents. and immunosuppressive medications, and high dose corticosteroids (more than 1 milligram per kilogram). * Children with contraindications of enteral feeding. * Children with gastrointestinal bleeding. * Children with open wounds following major surgery. * Children with short gut syndrome.

Primary outcome measure(s)

  • Incidence of ventilator-associated pneumonia — During the first 28 days after initiation of mechanical ventilation
    Incidence of ventilator-associated pneumonia (VAP) diagnosed according to predefined CDC/NHSN pediatric criteria

Trial sites (1)

FacilityCityRegionStatus
Tanta University Tanta Al Gharbia Recruiting

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Other trials for the same condition

Role of Lactoferrin in Prevention of Ventilator Associated Pneumonia in Neonates. Recruiting
Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07848165 on ClinicalTrials.gov ↗ ← All trials in Egypt