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Clinical Trials in Egypt / NCT07356869
Recruiting Not applicable

Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children

NCT07356869 · tracked via the Priya Life Science Egypt tracker
Sponsor
Al-Azhar University
Phase
Not applicable
Started
2025-08-15
Last updated
2026-01-21

Condition(s) studied

ProbioticEthyl Lauroyl ArginateMouthwashesStreptococcus MutansDental PlaqueSalivary pHChildren

Investigational drug(s) / intervention(s)

Probiotic mouthwashEthyl lauroyl arginate mouthwashProfessional prophylaxis (scaling + polishing)

Probiotic mouthwash: Patients will be receive probiotic mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.

Ethyl lauroyl arginate mouthwash: Patients will be treated with ethyl lauroyl arginate mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.

Professional prophylaxis (scaling + polishing): Patients will receive professional prophylaxis (scaling + polishing) at baseline and will use only regular toothpaste twice daily, with no adjunctive mouthwashes over 28 days.

Study summary

This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of Egyptian schoolchildren.

Eligibility

Sex
ALL
Min age
6 Years
Max age
12 Years
Healthy volunteers
No
Inclusion Criteria: * Healthy Egyptian schoolchildren aged 6-12 years. * Good general health. * Mild to moderate dental plaque accumulation. * Parental/caregiver willingness to provide consent Exclusion Criteria: * Antibiotic or antimicrobial use within the last month. * Allergies to the mouthwash components. * Systemic diseases affecting oral health. * Orthodontic appliances or extensive dental restorations.

Primary outcome measure(s)

  • S. mutans count — 28 days post-intervention
    S. mutans count will be measured at baseline (0 day) and post-intervention (28 days).

Trial sites (1)

FacilityCityRegionStatus
Al-Azhar University (Faculty of Dentistry) Cairo Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07356869 on ClinicalTrials.gov ↗ ← All trials in Egypt