Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children
Condition(s) studied
Investigational drug(s) / intervention(s)
Dental anesthesia: The intervention consists of pre-cooling and/or a sweet-tasting solution, used alone or in combination with topical local anesthesia, before administration of the dental local anesthetic injection.
Study summary
The study aims to determine whether pre-cooling and sweet-tasting solutions, alone or combined with topical anesthesia, provide better pain control during dental local anesthesia in children.
It has two phases:
Phase 1: Identify the children's preferred sweet-tasting solution among xylitol, monk fruit, erythritol, and honey.
Phase 2: A randomized controlled trial comparing 7 groups involving pre-cooling, sweet solution, topical anesthesia, and their combinations.
The primary outcome is pain measured by VAS, while secondary outcomes include SEM behavioral response, heart rate, and oxygen saturation. The planned sample is 220 children.
Eligibility
Primary outcome measure(s)
- Visual Analog Scale (VAS) — Immediately after intervention
Pain Intensity assessed by visual analogue scale
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Faculty of Dentistry, British University in Egypt | Cairo | El Sherouk | Recruiting |
More British University In Egypt trials in Egypt
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07835191 on ClinicalTrials.gov ↗ ← All trials in Egypt