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Clinical Trials in Egypt / NCT07817537
Recruiting Early Phase 1

Evaluating the Effectiveness of Intramuscular Versus Intravenous Tranexamic Acid for Minimizing Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial

NCT07817537 · tracked via the Priya Life Science Egypt tracker
Sponsor
Alexandria University
Phase
Early Phase 1
Started
2026-01-15
Last updated
2026-09-14

Condition(s) studied

Blood Loss After a Total Hip Replacement

Investigational drug(s) / intervention(s)

Tranexamic Acid (TXA) intarmuscularTranexamic Acid (TXA) intravenous →

Tranexamic Acid (TXA) intarmuscular: Tranexamic acid 1 gram administered via deep intramuscular injection into the lateral thigh or deltoid muscle prior to surgery.

Tranexamic Acid (TXA) intravenous: Tranexamic acid 1 gram administered intravenously over 10 minutes, following standard protocols, prior to surgery.

Study summary

Intramuscular vs. Intravenous Tranexamic Acid for Total Hip Arthroplasty

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: 1. Adult patients aged 18 years and older. 2. Scheduled to undergo elective primary total hip arthroplasty. 3. Able to provide informed consent. Exclusion Criteria: * 1\. History of renal failure or kidney transplant. 2. History of an arterial thromboembolic event (such as myocardial infarction or stroke) within the past year. 3\. Placement of an arterial stent within the past year. 4. History of deep venous thrombosis (DVT) or pulmonary embolism (PE). 5. Known contraindications to tranexamic acid. 6. Pregnancy or breastfeeding. 7. Refusal to participate or refusal to consent to receive blood products.

Primary outcome measure(s)

  • Change of Hemoglobin Concentration — From baseline (preoperative) up to hospital discharge (typically 3-5 days postoperatively).

Trial sites (1)

FacilityCityRegionStatus
Alexandria university main hospitals Alexandria Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07817537 on ClinicalTrials.gov ↗ ← All trials in Egypt