Unipolar radiofrequency ablation: Patients will undergo radiofrequency ablation (RFA) of three genicular nerves (superior medial, superior lateral and inferior medial) with one cannula.
Bipolar radiofrequency ablation: Patients will undergo radiofrequency ablation (RFA) as unipolar RFA but with two cannulas.
Study summary
This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.
Eligibility
Sex
ALL
Min age
50 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Age \> 50 years.
* Both genders.
* Diagnosed with chronic knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria and confirmed with plain radiography as the gold standard for the diagnosis of KOA.
* One chronic KOA pain not responding to other treatments as physiotherapy, oral analgesics, and intraarticular injection with hyaluronic acids or steroids.
* Kellgren-Lawrence grade (II-IV).
Exclusion Criteria:
* Chronic knee pain induced by infection, inflammation, tumors, and fractures.
* Prior knee surgery.
* Acute knee pain.
* Connective tissue diseases.
* Neurologic or psychiatric disorders.
* Intra-articular knee corticosteroid or hyaluronic acids in the past 3 months.
* Anticoagulant medication.
* Local infection of the site of intervention.
* Cognitive impairment.
Primary outcome measure(s)
Proportion of successful responders with a reduction 50% of pain — 24 weeks after the procedure The proportion of successful responders with a reduction 50% of Visual Analog Scale (VAS) will be recorded.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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