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Clinical Trials in Egypt / NCT07789340
Recruiting Not applicable

Unipolar Versus Bipolar Radiofrequency Ablation in Knee Osteoarthritis Pain

NCT07789340 · tracked via the Priya Life Science Egypt tracker
Sponsor
Tanta University
Phase
Not applicable
Started
2026-08-29
Last updated
2026-11-04

Condition(s) studied

Bipolar Radiofrequency AblationUnipolar Radiofrequency AblationKnee OsteoarthritisPain

Investigational drug(s) / intervention(s)

Unipolar radiofrequency ablationBipolar radiofrequency ablation

Unipolar radiofrequency ablation: Patients will undergo radiofrequency ablation (RFA) of three genicular nerves (superior medial, superior lateral and inferior medial) with one cannula.

Bipolar radiofrequency ablation: Patients will undergo radiofrequency ablation (RFA) as unipolar RFA but with two cannulas.

Study summary

This study aims to compare the efficacy of unipolar versus bipolar radiofrequency ablation (RFA) in knee osteoarthritis pain.

Eligibility

Sex
ALL
Min age
50 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age \> 50 years. * Both genders. * Diagnosed with chronic knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria and confirmed with plain radiography as the gold standard for the diagnosis of KOA. * One chronic KOA pain not responding to other treatments as physiotherapy, oral analgesics, and intraarticular injection with hyaluronic acids or steroids. * Kellgren-Lawrence grade (II-IV). Exclusion Criteria: * Chronic knee pain induced by infection, inflammation, tumors, and fractures. * Prior knee surgery. * Acute knee pain. * Connective tissue diseases. * Neurologic or psychiatric disorders. * Intra-articular knee corticosteroid or hyaluronic acids in the past 3 months. * Anticoagulant medication. * Local infection of the site of intervention. * Cognitive impairment.

Primary outcome measure(s)

  • Proportion of successful responders with a reduction 50% of pain — 24 weeks after the procedure
    The proportion of successful responders with a reduction 50% of Visual Analog Scale (VAS) will be recorded.

Trial sites (1)

FacilityCityRegionStatus
Tanta University Tanta El-Gharbia Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07789340 on ClinicalTrials.gov ↗ ← All trials in Egypt