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Clinical Trials in Egypt / NCT07785973
Recruiting Not applicable

Effect of NeoSEALER FLO and AH Plus Resin Sealer on Postoperative Pain and Healing of Periapical Lesions

NCT07785973 · tracked via the Priya Life Science Egypt tracker
Sponsor
Minia University
Phase
Not applicable
Started
2026-08-01
Last updated
2026-08-25

Condition(s) studied

Post Operative Pain

Investigational drug(s) / intervention(s)

AH plus sealer

AH plus sealer: to evaluate and compare postoperative pain and periapical healing after root canal treatment using two different base endodontic sealers: * NeoSEALER Flo * AH plus Resin sealer

Study summary

Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success of root canal treatment is affected by the correct choice of clinical protocol.

These factors are dependent on the sanitization process (instrumentation, irrigating solution, irrigating strategies, and intracanal dressing) the apical limit of the root canal preparation and obturation, and the quality of the sealer. The challenges affecting the healing process of endodontically treated teeth include control of the inflammation of pulp or infectious processes and simultaneous neutralization of unpredictable provocations to the periapical tissue.

Eligibility

Sex
ALL
Min age
20 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Patients with mature permanent teeth. * Patients with apical periodontitis. * Maxillary anterior teeth only will be involved. * Patients should be free from any systemic disease that may affect normal healing and predictable outcome. * Patients who will agree to the consent and will commit to follow-up period. * The selected teeth should have periapical lesion score ≤3 Exclusion Criteria: * Patients with immature canals. * Patients with swelling. * Pregnant females. * Patients who could/would not participate in a 1-year follow-up. * Geriatric patients. * Patients with old age. * Teeth with periodontal involvement. * Teeth with vertical root fractures. * Non-restorable teeth. * cases with previously initiated endodontic treatment.

Primary outcome measure(s)

  • Treatment of Postoperative Pain — from 0 hours to 2 weeks after the procedure
    Patients will be evaluated for postoperative pain via (NRS) to record the intensity of pain.as follows: 0 reading represents "no pain" ; 1- 3 reading represents "mild pain" ; 4- 6 reading represents "moderate pain" and 7- 10 reading represents "severe pain".

Trial sites (1)

FacilityCityRegionStatus
Minia University, Faculty of Dentistry Minya Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07785973 on ClinicalTrials.gov ↗ ← All trials in Egypt