Effect of Aerobic and Resistance Exercise on Quarry Workers

Condition(s) studied

Investigational drug(s) / intervention(s)

Aerobic exercise training: participants will receive aerobic exercise training in addition to routine medical treatment and breathing exercise training.

Resistance exercise training: participants will receive resistance exercise training in addition to routine medical treatment and breathing exercise training.

Study summary

The goal of this randomized clinical trial is to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers. It will also evaluate their effects on functional capacity and health-related quality of life (HRQOL).

The main questions it aims to answer are:

Does aerobic exercise training improve ventilatory function more effectively than resistance exercise training? How do aerobic and resistance exercise training affect functional capacity and health-related quality of life in quarry workers?

Researchers will compare aerobic exercise training and resistance exercise training with a control group receiving routine treatment and breathing exercises to determine which intervention is more effective in improving ventilatory function, functional capacity, and health-related quality of life.

Participants will:

Be randomly assigned to one of three groups: an aerobic exercise training group, a resistance exercise training group, or a control group.

Receive the assigned intervention three times per week for eight consecutive weeks.

Undergo ventilatory function assessment using spirometry. Complete assessments of functional capacity and health-related quality of life before and after the intervention.

Eligibility

Primary outcome measure(s)

• Forced Expiratory Volume in One Second (FEV1) — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
  Forced Expiratory Volume in One Second (FEV1) will be assessed using spirometry. FEV1 is the volume of air forcefully exhaled during the first second of a forced expiratory maneuver and is expressed in liters (L). Higher values indicate better airway function and ventilatory performance.
• Forced Vital Capacity (FVC) — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
  Forced Vital Capacity (FVC) will be assessed using spirometry. FVC is the maximum volume of air that can be forcefully exhaled after a full inspiration and is expressed in liters (L). Higher values indicate better ventilatory function.
• Forced Expiratory Volume in One Second to Forced Vital Capacity Ratio (FEV1/FVC) — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
  The FEV1/FVC ratio will be assessed using spirometry and expressed as a percentage (%). This parameter reflects the proportion of the forced vital capacity exhaled during the first second of expiration and is commonly used to evaluate airflow limitation. Higher values generally indicate better ventilatory function.
• Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%) — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)
  Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%) will be assessed using spirometry. FEF25-75% represents the average expiratory flow during the middle half of the forced vital capacity maneuver and is expressed in liters per second (L/s). It is considered a sensitive indicator of small airway function. Higher values indicate better small airway function and ventilatory performance.
• Maximum Voluntary Ventilation (MVV) — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
  Maximum Voluntary Ventilation (MVV) will be assessed using spirometry. MVV is the maximum volume of air inhaled and exhaled voluntarily within one minute and is expressed in liters per minute (L/min). Higher values indicate better respiratory muscle endurance and ventilatory capacity.
• Health-Related Quality of Life — Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
  Health-related quality of life will be assessed using the St. George's Respiratory Questionnaire (SGRQ). The SGRQ consists of 50 items grouped into three domains: Symptoms, Activity, and Impacts. Total scores range from 0 to 100, with higher scores indicating poorer health-related quality of life. Lower scores represent better outcomes

Trial sites (1)

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