Photodynamic Therapy for Preventing Recurrent Chromogenic Stains on Deciduous Teeth

Condition(s) studied

Investigational drug(s) / intervention(s)

Antimicrobial Photodynamic Therapy: Conventional prophylaxis followed by topical application of methylene blue activated by 660-nm red light for antimicrobial photodynamic therapy.

Conventional Prophylaxis: Standard mechanical prophylaxis using rubber-cup polishing and prophylaxis paste.

Study summary

Chromogenic extrinsic stains are common in children and frequently recur following conventional prophylaxis. Antimicrobial photodynamic therapy (aPDT) using methylene blue activated by red light has demonstrated antimicrobial activity against oral biofilm and may reduce stain recurrence. This pilot controlled clinical trial aims to compare conventional prophylaxis combined with methylene blue-mediated antimicrobial photodynamic therapy with conventional prophylaxis alone for preventing recurrent chromogenic extrinsic stains on deciduous teeth.

Eligibility

Primary outcome measure(s)

• Recurrence of Chromogenic Extrinsic Stains — 6 months after treatment
  Recurrence of chromogenic extrinsic stains assessed by standardized clinical visual examination and recorded as the presence or absence of visible chromogenic extrinsic staining at the 6-month follow-up visit.

Trial sites (1)

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