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Clinical Trials in Egypt / NCT07732127
Recruiting Not applicable

Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers

NCT07732127 · tracked via the Priya Life Science Egypt tracker
Sponsor
Menoufia University
Phase
Not applicable
Started
2026-07-01
Last updated
2026-08-12

Condition(s) studied

Initial Caries

Investigational drug(s) / intervention(s)

Fluorescent Starch Nano-particles

Fluorescent Starch Nano-particles: The evaluation of the diagnostic accuracy of LumiCare mouth rinse combined with salivary biomarkers for the early detection of initial enamel caries and to compare its diagnostic performance with conventional clinical diagnostic methods.

Study summary

Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early stage. Therefore, early detection of carious lesions is essential to implement preventive and minimally invasive treatment strategies before irreversible tooth destruction occurs.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: \- Presence of at least one suspected initial enamel carious lesion. Exclusion Criteria: * Cavitated carious lesions * Previous restorative treatment on the examined tooth * Antibiotic therapy during the previous month, * Systemic diseases affecting salivary secretion * Xerostomia or salivary gland disorders

Primary outcome measure(s)

  • Diagnosis of Initial Caries — immediately after the intervention
    Evaluation of the participants by Using Fluorescent Starch Nano-particles and Salivary Biomarkers in early detection of initial caries

Trial sites (1)

FacilityCityRegionStatus
Menoufia Dental Hospital Shibīn al Kawm Menoufia Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07732127 on ClinicalTrials.gov ↗ ← All trials in Egypt