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Clinical Trials in Egypt / NCT07672847
Enrolling by invitation Not applicable

Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials

NCT07672847 · tracked via the Priya Life Science Egypt tracker
Sponsor
Menoufia University
Phase
Not applicable
Started
2026-01-31
Last updated
2026-06-29

Condition(s) studied

DentureCAD/CAMStabilityPEEKPMMA

Investigational drug(s) / intervention(s)

M0 groupM1 group : PMMA+ Sodium hypochloriteM2 group: PMMA+ ChlorhexidineM3 group : PMMA + Effervescent Alkaline Peroxide TabletE0 group : PEEK control groupE1 group : PEEK + Sodium hypochloriteE2 group : PEEK +Chlorhexidine groupE3 group: PEEK + Effervescent Alkaline Peroxide Tablet

M0 group: Immersed in distilled water at 37 c for 6 months

M1 group : PMMA+ Sodium hypochlorite: Immersed in 1% sodium hypochlorite solution for 6 months

M2 group: PMMA+ Chlorhexidine: Immersed in 0.2% chlorhexidine solution for 6 months

M3 group : PMMA + Effervescent Alkaline Peroxide Tablet: Immersed in Effervescent tablet denture cleanser solution for 6 months

E0 group : PEEK control group: Immersed in distilled water at 37 c for 6 months

E1 group : PEEK + Sodium hypochlorite: Immersed in 1% sodium hypochlorite solution for 6 months

E2 group : PEEK +Chlorhexidine group: Immersed in 0.2% chlorhexidine solution for 6 months

E3 group: PEEK + Effervescent Alkaline Peroxide Tablet: Immersed in Effervescent tablet denture cleanser solution for 6 months

Study summary

This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to manufacturer's instructions- on surface roughness , microhardness and dimensional stability (%) of CAD-CAM Milled both Polymethyl methacrylate and Polyether Ether Ketone denture base materials.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Used prefabricated CAD-CAM blocks (PMMA and PEEK, dental grade) * All specimens milled using standardized CAD-CAM protocols * Materials from same brand, batch and shade per group * All specimens polished to a clinical high gloss standard * Used standardized specimen geometry Exclusion Criteria: * Specimens fabricated using a method other than CAD-CAM milling * Use blocks from different manufacturer, batches or shades within the same test group * Use specimens with fabrication defects (visible porosity, cracks, internal voids) or obvious milling errors (tool chattering marks, incomplete milling) * Specimens with dimensional inaccuracy * Specimens subjected to incorrect immersion time, temp or concentration of disinfectant * Use contaminated, not freshly prepared or expired disinfectant solutions

Primary outcome measure(s)

  • Surface Roughness Measurement — 6 months
    Surface roughness (Ra) was measured using a profilometer. Each specimen was scanned at three random locations, and the mean value was recorded. The device was calibrated using the manufacturer's reference standard prior to each measurement session.

Trial sites (1)

FacilityCityRegionStatus
Menoufia University Shibīn al Kawm Egypt

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Other trials for the same condition

Clinical Evaluation of 3D-Printed Resin Versus CAD/CAM-Milled Lithium Disilicate Overlay Restorations Enrolling by invitation
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07672847 on ClinicalTrials.gov ↗ ← All trials in Egypt