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Clinical Trials in Egypt / NCT07612540
Starting soon Not applicable

Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial

NCT07612540 · tracked via the Priya Life Science Egypt tracker
Sponsor
Cairo University
Phase
Not applicable
Started
2026-06-01
Last updated
2026-05-28

Condition(s) studied

Dental Caries

Investigational drug(s) / intervention(s)

phosphoric acid pretreatment

phosphoric acid pretreatment: surface treatment with Bioactive Glass Air Abrasion giomer based fissure sealnt will be applied after surface treatment With laser

Study summary

This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years. The study compares sealant application with and without diode laser conditioning on molars with ICDAS 0-2 fissures over a 12-month follow-up period. Primary outcome is sealant retention using Simonsen's criteria, while secondary outcome is caries prevention using modified USPHS criteria. The study hypothesizes that diode laser pre-treatment may improve sealant retention and enhance caries prevention by modifying enamel surface characteristics and improving sealant penetration.

Eligibility

Sex
ALL
Min age
17 Years
Max age
22 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Young adult Patients Aged 17-22. * Good oral hygiene (plaque index score 0 or 1). * Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing). * Patients approving to participate in the study. Exclusion Criteria: * •Patients with known allergic or adverse reaction to the tested materials. * Systematic disease that may affect participation. * Xerostomic patients.

Primary outcome measure(s)

  • Loss of sealant's retention — 1 year
    Simonsen's criteria Full retention (FR) The material was fully present on the occlusal surfaces Partially lost (PL) The material was present, but as a result of either wear or loss of the material, part of a previously sealed pit or fissure, or both, was exposed- Totally lost (TL) No trace of the material was detected on the surface.

Trial sites (3)

FacilityCityRegionStatus
Faculty of Dentistry Cairo University Cairo Egypt
Faculty of Dentistry Cairo Egypt
Yomna Cairo Egypt

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Other trials for the same condition

Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite Enrolling by invitation
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars Starting soon
Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients Recruiting
Comparing Two Brands of Silver Diamine Fluoride for Stopping Cavities in Children Active, not recruiting
Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children. Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07612540 on ClinicalTrials.gov ↗ ← All trials in Egypt