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Clinical Trials in Egypt / NCT07474194
Recruiting Phase 4

Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section

NCT07474194 · tracked via the Priya Life Science Egypt tracker
Sponsor
Beni-Suef University
Phase
Phase 4
Started
2025-09-20
Last updated
2026-03-16

Condition(s) studied

Infection Control / MethodsSurgical Site Infection (SSI)

Investigational drug(s) / intervention(s)

Clindamycin vaginal creamVaginal preparation with povidone- iodide solution 10 %

Clindamycin vaginal cream: Clindamycin vaginal cream one applicator each night for 3 nights before CS.

Vaginal preparation with povidone- iodide solution 10 %: Vaginal preparation with povidone- iodide solution 10 %

Study summary

To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
40 Years
Healthy volunteers
No
Inclusion Criteria: * female participants with singleton pregnancies scheduled for elective cesarean sections at term, specifically between 37 and 40 weeks of gestation * free from any medical disorders. * The participants' ages ranged from 18 to 40 years * body mass index (BMI) ranged from 18 to 30 kg/m2 Exclusion Criteria: 1. Cases of urgent or emergent CS. 2. Abnormal vaginal secretion (bad smelling yellowish secretion, whitish cheesy discharge with pruritus, bloody discharge; etc…). 3. Women with medical disorders such as pre-gestational diabetes, anemia, hypertension, preeclampsia, or immunosuppressant pregnant women. 4. Women who had a skin infection adjacent to the operative site. 5. Allergy to topical povidone-iodine or clindamycin 6. Feverish patients or history of premature rupture of membranes or with placenta previa. 7. patients lost during follow-up were excluded from the final analysis.

Primary outcome measure(s)

  • Wound infection (surgical site infection SSI) — 3 weeks
    erythema, tenderness or wound edge separation with purulent discharge involving the cesarean incision site.

Trial sites (1)

FacilityCityRegionStatus
Beni suef university Banī Suwayf Egypt Recruiting

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Other trials for the same condition

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07474194 on ClinicalTrials.gov ↗ ← All trials in Egypt