Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Clinical Trials in Egypt / NCT07452315
Active, not recruiting Not applicable

Comparaison of the Accuracy of Immediate Fibula Reconstruction With Implants in Fresh Versus Delayed Cases

NCT07452315 · tracked via the Priya Life Science Egypt tracker
Sponsor
Cairo University
Phase
Not applicable
Started
2026-01-02
Last updated
2026-03-05

Condition(s) studied

Mandible Reconstruction

Investigational drug(s) / intervention(s)

fibula free flap

fibula free flap: Immediate reconstruction with the use of PSIs and dental implants in fresh and delayed cases

Study summary

The goal of this clinical trial is to learn if mandibular reconstruction with immediate dental implants is as accurate in fresh cases and delayed cases

The accuracy of the fibular segments and dental implants will be compared in both groups

Participants will:

undergo a preoperative CT scan with VSP for mandibular reconstruction Undergo the surgical procedure Undergo an immediate postoperative CT scan and have it superimposed on the virtual plan to detect inaccuracies

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria for participants: * Adult patients with conditions requiring mandibular reconstruction using fibula free flaps. * Adult patients diagnosed with neoplastic conditions requiring resection and agreed to immediate reconstruction * Adult patients with segmental mandibular defects resulting from previous pathology, trauma, infectious conditions * Patients willing for the surgical procedure and follow-up, with an informed consent. Exclusion Criteria for participants: * Patients with significant medical diseases and comorbidities preventing them undergoing lengthy procedures under general anesthesia * Patients with Peripheral Vascular Disease * Patient with known allergy to contrast media in whom a CTA of the lower limbs will not be possible * Patients with Peronea Magna where the peroneal artery is the main blood supply of the lower limbs and its harvesting might result in compromise of the leg vascularity * Patients with no desire for surgical correction * Patients with any diseases that compromise bone or soft tissue healing. Patients with local pathosis that interfere with the bone healing.

Primary outcome measure(s)

  • Accuracy of the fibular segments and dental implants — From enrollment "VSP" till the immediate postoperative CT, Throughout the completion of the study, for an average of 1 year
    Accuracy of the fibular segments and dental implants in patients compared to the Virtual Surgical plan, Measured in degrees and millimeters

Trial sites (1)

FacilityCityRegionStatus
Faculty of Oral and dental medicine Giza الجيزة

More Cairo University trials in Egypt

The Link Between Periodontitis, Smoking and Oral Cancer Starting soon
Treating Intrabony Defect With MINST VS MINST Extended PRF Recruiting
Respiratory Exercises Versus Deep Neck Flexor Training in Chronic Mechanical Neck Pain Recruiting
Integrating Aerobic, Respiratory, and Cognitive Training in Acute Heart Failure Starting soon
Preparation Time Of Bioflx Crowns Compared To Zirconia Crowns On Primary Molars Starting soon

Other trials for the same condition

Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07452315 on ClinicalTrials.gov ↗ ← All trials in Egypt