Ireland
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Recruiting Observational

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

NCT07347925 · tracked via the Priya Life Science Egypt tracker
Phase
Observational
Started
2026-01-10
Last updated
2026-01-16

Condition(s) studied

Heart Failure

Investigational drug(s) / intervention(s)

Prehospital ARNI useNo prehospital ARNI use

Prehospital ARNI use: Participants who were using ARNI therapy before hospital admission

No prehospital ARNI use: Participants who were not using ARNI therapy before hospital admission

Study summary

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes.

The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital.

Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * \>= 18 years, male or female EF \<40% Exclusion Criteria: * EF\>40% Pregnancy or breastfeeding

Primary outcome measure(s)

  • In-hospital cardiac and renal events — 3 months

Trial sites (1)

FacilityCityRegionStatus
Mansoura university Hospital Al Mansurah Egypt Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07347925 on ClinicalTrials.gov ↗ ← All trials in Egypt