Correlation Between Vaspin Gene Polymorphism and Serum Vaspin Levels in Psoriasis Vulgaris
Condition(s) studied
Investigational drug(s) / intervention(s)
vaspin gene polymorphism: to detect the correlation between vaspin gene polymorphism and serum vaspin levels among psoriasis patients. * To detect the relationship between the risk of psoriasis and the vaspin gene polymorphism. * To detect correlation between vaspin gene polymorphism and the severity of psoriasis.
Study summary
Psoriasis is a common immune-mediated inflammatory skin disease affecting at least 100 million individuals worldwide. In Egypt, the prevalence of psoriasis ranges between 0.19% and 3% of the Egyptian people.
It is associated with poor quality of life, reduced life expectancy and multimorbidity including psoriatic arthritis, obesity and cardiovascular disease.
Vaspin (VASP, SERPIN 12) is a recently discovered adipokine that has been isolated from the visceral adipose tissue of a rat model of type 2 diabetes. It is coded by the gene SERPNA12 located on the long arm of chromosome 14q32.13 and consists of six exons and five introns.
Eligibility
Primary outcome measure(s)
- Detection of vaspin gene polymorphism — 12 Months
Assessment of vaspin gene polymorphism in psoriasis patients to determine the disease severity
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Aswan University Hospital | Aswān | Egypt | Recruiting |
More Aswan University trials in Egypt
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07320872 on ClinicalTrials.gov ↗ ← All trials in Egypt