Ireland
--:--IST
Enrolling by invitation Not applicable

Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion

NCT07140003 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-07-01
Last updated
2025-08-24

Condition(s) studied

Pleural Tissue Culture

Investigational drug(s) / intervention(s)

pleural biopsy

pleural biopsy: To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.

Study summary

comparison between the result of fluid culture and that of pleural tissue culture

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Exudate neutrophilic pleural fluid aspirate, or met at least one or more of the following criteria: grossly frank purulent, gram stain positive for bacteria, bacterial culture positive, acidic with a pH \<7.20, low pleural fluid glucose (\<55mg/dL), and CT evidence of pleural infection. Exclusion criteria: Pleural infections by Mycobacterium tuberculosis.Malignant effusion.Coagulation defects.

Primary outcome measure(s)

  • initial pleural fluid and parietal pleural tissue — 2 weeks
    the result of culture
  • result of culture — one month
    the result of pleural fluid culture and the pleural tissue culture result

Trial sites (1)

FacilityCityRegionStatus
Chest Department -Faculty of Medicine Alexandria Chest Department
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07140003 on ClinicalTrials.gov ↗ ← All trials in Egypt