Effect of Minoxidil Solution Iontophoresis on Androgenic Alopecia

Condition(s) studied

Investigational drug(s) / intervention(s)

Minoxidil solution iontophoresis: The half of the scalp of the participants will be treated with 5% minoxidil solution through Iontophoresis that will be applied at small low voltage (typically 10 V or less) continuous constant current (typically 0.5 mA/cm2 or less) to push a charged drug into skin or other tissue, twice daily at home.

saline solution iontophoresis: The other half of the scalp of the participants will be treated with placebo saline solution ( control) with the current application.

Study summary

The aim of the study is to evaluate the therapeutic efficiency of minoxidil solution iontophoresis on Androgenic Alopecia.

Eligibility

Primary outcome measure(s)

• Change in the number of hair follicles — 12 weeks
  Trichoscopy will be used to detect the change in the number of hair follicles as a comparison between before and after intervention. Trichoscopy helped with the definitive diagnosis of Alopeacia in patients for whom the clinical diagnosis was doubtful, which was confirmed by histopathology. Thus trichoscopy is a noninvasive, sensitive and specific investigation that is valuable in women with alopecia, the cause of which is otherwise very difficult to assess clinically, and it has a definite role in the diagnosis of cases with an atypical clinical picture.Trichoscopy results were obtained in frontal, occipital and both temporal areas of scalp, including number of yellow dots and vellus hairs, number of hairs in one pilosebaceous unit and percentage of follicular ostia with perifollicular hyperpigmentation.

Trial sites (1)

More Cairo University trials in Egypt