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Starting soon Phase 2

Micro-Needling Technique Using Ozonated Olive Oil in Periodontal Diseases

NCT06990282 · tracked via the Priya Life Science Egypt tracker
Phase
Phase 2
Started
2025-07-01
Last updated
2025-05-25

Condition(s) studied

Periodontal DiseasesPeriodontitis and Treatment NeedGingivitis

Investigational drug(s) / intervention(s)

microneedlingscalingOzonated olive oil

microneedling: gingival microneedling (small holes in gingiva)

scaling: scaling (plaque removal)

Ozonated olive oil: ozonated olive oil after microneedling

Study summary

The research idea is based on using micro-acupuncture therapy with ozone-treated olive oil to improve the condition of patients suffering from gingivitis and periodontitis and comparing it to the scientifically proven conventional treatment. This is a randomized controlled study, and this idea was chosen from the current general trend in medicine, particularly in dentistry, to use natural sources for treatment due to fewer side effects compared to the chemicals used.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-60 years old * Male and female medically free participants * Patients suffering from biofilm induced gingivitis or periodontitis Exclusion Criteria: * Smoking and tobacco related habits * Non-biofilm induced gingival diseases * Necrotizing periodontal diseases * periodontitis as a manifestation of systemic disease * Third molar tooth

Primary outcome measure(s)

  • bleeding on probing — 4 weeks
    Muehlemann \& Son index
  • Plaque index — 4 weeks
    Silness-Loe Plaque Index
  • probing depth and clinical attachment loss — 4 weeks
    measured in mm using a UNC 15 probe

Trial sites (1)

FacilityCityRegionStatus
Fayoum University Al Fayyum Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06990282 on ClinicalTrials.gov ↗ ← All trials in Egypt