Ireland
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Starting soon Phase 3

Clinical Comparison of Xenograft With Hydrogel Versus Xenograft Alone in the Socket Preservation After Tooth Extraction: A Randomized Controlled Clinical Trial

NCT06957197 · tracked via the Priya Life Science Egypt tracker
Phase
Phase 3
Started
2025-09-22
Last updated
2025-05-04

Condition(s) studied

Socket Perservation

Investigational drug(s) / intervention(s)

Hydrogel with xenograftXenograft →

Hydrogel with xenograft: vehicle to hold xenograft

Xenograft: to maintain the socket

Study summary

Clinical Comparison of xenograft with hydrogel versus xenograft alone in the socket preservation After tooth extraction: A Randomized controlled Clinical Trial The ideal scaffolds used for alveolar ridge preservation are supposed to show good biocompatibility, mechanical properties, and formability for irregularly shaped bone defects, as well as degradation rates matching bone growth . One of the most used synthetic scaffolds is hydrogel. Hydrogels owning three-dimensional cross-linked network structures have physical and chemical properties like human tissues . They can not only simulate the extracellular matrix (ECM) of bone but also allow the storage, and transport of various growth factors, cytokines, and nutrients due to their high permeability .

Eligibility

Sex
ALL
Min age
16 Years
Max age
60 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Adult, systemically healthy patients with hopeless infected teeth and nonrestorable remaining structure or root. Exclusion Criteria: * Systemic or local disease/ condition that would compromise post-operative healing (e.g. Diabetics, patients who in need for systemic corticosteroids).

Primary outcome measure(s)

  • Quantity of bone (bone height) — 3 mounths
    Method of Measurement ;Radiographically Unit of Measurement ;mm

Trial sites (1)

FacilityCityRegionStatus
Cairo University Cairo Cairo Governorate
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06957197 on ClinicalTrials.gov ↗ ← All trials in Egypt