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Clinical Trials in Egypt / NCT06889181
Starting soon Not applicable

Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate

NCT06889181 · tracked via the Priya Life Science Egypt tracker
Sponsor
Cairo University
Phase
Not applicable
Started
2025-04-01
Last updated
2025-03-21

Condition(s) studied

Cleft PalatePlasma Rich in Growth Factors

Investigational drug(s) / intervention(s)

Plasma Rich in Growth Factors (PRGF)Placebo

Plasma Rich in Growth Factors (PRGF): using prgf with closing primary cleft palate - isolated cleft palate Minutes before the surgery, 10-20 ml of venous blood from each patient. -The blood is centrifuged to obtain PRGF. -Fixed between nasal and palatal mucosa

Placebo: primary closing cleft palate-isolated cleft palate

Study summary

Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?

Eligibility

Sex
ALL
Min age
6 Months
Max age
18 Months
Healthy volunteers
Accepted
Inclusion Criteria: * systemically healthy patients (American Society of Anesthesiologists -ASA I and II); not older than 6-18 months * Patients with primary non-syndromic isolated cleft palate * Apprehensive to be in the study. Exclusion Criteria: * Patients with recurrent palatal fistula * Existence of syndromic cleft palate * Blood diseases and platelet disorders (hematological disease) * Systematic disease radiotherapy or chemotherapy for malignancy

Primary outcome measure(s)

  • wound healing assesment (edema at 5th day post operatively) — first day after surgery, 3rd day, and 5th day
    clinical records, percentage of persistence of edema number of participants with percentage of persisting of edema

Trial sites (1)

FacilityCityRegionStatus
Faculty of Dentistry, Cairo University Manial Cairo Governorate

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Other trials for the same condition

Effect of Furlow Palatoplasty With Buccal Myomucosal Flap on the Speech Development Recruiting
Nebulized Bupivacaine Analgesia for Cleft Palate Repair Recruiting
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06889181 on ClinicalTrials.gov ↗ ← All trials in Egypt