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Clinical Trials in Egypt / NCT06835842
Recruiting Not applicable

Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia

NCT06835842 · tracked via the Priya Life Science Egypt tracker
Sponsor
Cairo University
Phase
Not applicable
Started
2025-03-10
Last updated
2025-07-10

Condition(s) studied

Pneumonia

Investigational drug(s) / intervention(s)

rib mobilization techniqueroutine chest physiotherapy

rib mobilization technique: rib mobilization technique The patient in experimental group will be relaxed in semi- fowler position while connected to mechanical ventilator, therapist will seat at the patient "side, his fingers pads are placed at the position of the patient's rib angles , pulling upward and the lateral position the position is held while wait for the soft tissues to release this take from 15 seconds .Release of the diaphragm through manual contact with hypothenar region of therapist thumb inferior laterally xiphoid process and rest along Antero lateral costal margin below rib7 during exhalation the therapist thumb give pressure posteriorly repeat this steps for 3 to5 respiratory cycle • routine chest physiotherapy percussion on chest wall its frequency should be 3-7 beats per sec. vibration applying a light pressure with hand on affected segment for about 5 min modified postural drainage R. and L. side. U\&L limb passive ex. for R.10 x3 set .this program for 30 minutes once daily for ten days

routine chest physiotherapy: routine chest physiotherapy the patient will be laid in half supine position connected to a ventilator applying * percussion on chest wall its frequency should be 3-7 beats per second or 180-420 beats per minute * vibration applying a light pressure with flattened hand on affected segment for about 5 minutes * modified postural drainage (right and left sidling 10 min for each side * upper and lower limb exercise for 4 limbs (3 sets and each set has 10 repetition * this program for 30 minutes once daily * for 10 consecutive days

Study summary

this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters from mechanical ventilator in patients with pneumonia •

HYPOTHESES:

It will be hypothesized that there may be significant effect of rib mobilization on weaning parameters from mechanical ventilator in patients with pneumonia.

RESEARCH QUESTION:

Does rib mobilization have an effect on weaning parameters from mechanical ventilator in patients with pneumonia? measuring weaning parameters: on screen of mechanical ventilator : measuring respiratory rate, Tidal volume (TV), FiO2.

* Arterial blood gases (ABG) analyzer machine ABG is recorded daily (PH- PaO2 - PaCO2)
* Length of ICU stay: calculated by (admission date - discharge date
* Weaning success rate

Eligibility

Sex
ALL
Min age
40 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: 1. Patient's age ranged from 40- 50 years old from both genders. 2. Diagnosed with pneumonia and need invasive mechanical ventilation support. 3. Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O). 4. mean arterial pressure \> 75 mmHg and urine output \> 1 mL/kg/h; 5. Patients with Glasgow coma scale (GCS) \> 8T 6. Unconscious and semi-conscious patients. - Exclusion Criteria: 1. Unstable hemodynamics 2. Unstable neurological problems e.g. (epileptic seizures -hyperthermia). 3. Unstable chest wall e.g. (multiple rib or vertebral fractures) 4. Increase intracranial pressure (\>20 mmHg for \>5 min). 5. Undrained pneumothorax, recent pulmonary surgery

Primary outcome measure(s)

  • Arterial blood gases — at least 10 consecutive days
    • Arterial blood gases (ABG): (PH -PaO2 - PaCO2) • PaO2/FiO2 ratio (P/F): One element of predicting successful weaning from mechanical ventilation is PaO2/FiO2 \> 200
  • Respiratory rate (RR) — at least 10 consecutive days
    It will be measured using a mechanical ventilator.
  • Tidal volume (TV) — at least 10 consecutive days
    It will be measured using a mechanical ventilator.

Trial sites (1)

FacilityCityRegionStatus
El Galaa Military Hospital Cairo Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06835842 on ClinicalTrials.gov ↗ ← All trials in Egypt