Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide
Clinical Trials in Egypt / NCT06809829
Recruiting Not applicable

Evaluation of Doxycycline Nanoparticle With Gelatin Sponge on Immediate Implant in Esthetic Region

NCT06809829 · tracked via the Priya Life Science Egypt tracker
Sponsor
Kafrelsheikh University
Phase
Not applicable
Started
2025-02
Last updated
2025-02-05

Condition(s) studied

Immediate Implant Placement

Investigational drug(s) / intervention(s)

Immediate Implant Placement

Immediate Implant Placement: Eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline loaded gelatin nanoparticles along with gelatin sponge (group A) Eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline along with gelatin sponge (group B)

Study summary

The goal of this clinical trial is to Evaluate the effect of Doxycycline nanoparticles along with gelatin sponge in immediate implant cases in esthetic zone. The main question it aims to answer is:

Does the application of doxycycline nanoparticles with gelatin sponge improve the clinical and radiographic outcomes of immediate implant cases in esthetic zone?

Researchers will compare eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline loaded gelatin nanoparticles along with gelatin sponge (group A) with eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline along with gelatin sponge (group B). to see if the doxycycline loaded nanoparticles will improve the clinical and radiographic outcomes of the immediate implant .

Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\].

Eligibility

Sex
ALL
Min age
18 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * The presence of non-restorable single-rooted maxillary centrals, canines or premolars. * Sufficient bone volume. * Good oral hygiene. * The remaining space between the socket and the fixture equals or more than 2mm at the coronal third of the socket. * Sufficient bone width (≥ 1 mm) in the buccal plate of the remaining bone to place an implant confirmed by cone beam computer tomography (CBCT). Exclusion Criteria: * Insufficient bone volume. * Active infection. * Patients on chemotherapy or radiotherapy. * Patients who have systemic disorders {uncontrolled diabetes mellitus, autoimmune disease, …etc}, * Pregnant patients, * Patients with bone diseases * Presence of periapical pathology affecting the neighbouring teeth. * Smokers.

Primary outcome measure(s)

  • Marginal (crestal) bone loss (MBL). — after surgery and 6 months after surgery
    Radiographic examination of the patients will be done firstly pre-operative then just after the surgical procedures as a base point and at six months follow-up period post-operative by using CBCT (carestream 9600). On Demand3D program will be used for image reconstruction and analysis. For the calculation of marginal (crestal) bone loss (MBL), the implant will be used as a reference by adjusting the cross-sectional long axis in the center of the implant and bisecting it. A line will be drawn parallel to the implant, starting at the crest of the bony cortical plate of bone and ending at the apical level of the implant; height will be recorded in millimeters immediately and 6 months postoperative. The same process will be repeated from the palatal direction.

Trial sites (1)

FacilityCityRegionStatus
Faculty of dentistry kafrelsheikh university Kafrelsheikh Kafrelsheikh Recruiting

More Kafrelsheikh University trials in Egypt

Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty Recruiting
Incentive Spirometer Training and Oropharyngeal Motor Training for Pulmonary Dysfunction in Spastic Diplegic Children Active, not recruiting
Myoma Screw in Manipulation of Large Uterus in Total Laparoscopic Hysterectomy Starting soon
Effect of Pully System on Hemiplegic Children Starting soon
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries Recruiting

Other trials for the same condition

Immediate Implant Placement Using Xenograft Mixed with Vitamin D Versus Hyaluronic Acid. Recruiting
Labial Bone Thickness Around Immediate Implants in the Esthetic Zone Following a Novel Socket Evaluation System Starting soon
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant Recruiting
Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management Recruiting
Effect of Subepithelial Connective Tissue Graft With Socket Shield Technique Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06809829 on ClinicalTrials.gov ↗ ← All trials in Egypt