Ireland
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Recruiting Not applicable

Efficacy of Intra-Ureteric Aminophylline Installation After Failed Stone Accessibility by Semi-rigid Ureteroscopy. Prospective Trial

NCT06728943 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2024-12-01
Last updated
2024-12-11

Condition(s) studied

Ureterocopic LithotripsyStone UreterUreteric Stone

Investigational drug(s) / intervention(s)

ureteral dilatation

ureteral dilatation: Direct semi-rigid ureteroscopy will initially be attempted without endodilatation (KARL STORZ, 43 cm, 6°, 7 Fr.). On failure to advance the semi-rigid ureteroscope through the ureter, intra-ureteric instillation of 20 ml of aminophylline (250 mg/10 mL) through ureteric stent and another trial to pass the same scope will be done after 10 minutes of intra-ureteral aminophylline instillation.

Study summary

In this study we will test the effect of local intraureteric aminophylline instillation through Ureteric stent and Reaching stone without the need of ballon dilataion

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * The study will include patients with failed stone accessibility by semi-rigid ureteroscopy. Exclusion Criteria: * Child age group * Pre stented patients * Contraindications to aminophylline (hypersensitivity to drug components, pregnancy or lactation ,…) * Contraindications to ureteroscopy (active urinary tract infection - Contraindications to general or spinal anesthesia - Uncorrected bleeding disorders)

Primary outcome measure(s)

  • Success rate of Ureteral access and Scoping of the stones after Intra-ureteral instillation of Aminophylline without Ballon Dilatation — from the start of ureteroscopy entrance to the end of the procedure
    Success rate of Ureteral access and Scoping of the stones after Intra-ureteral instillation of Aminophylline without Ballon Dilatation

Trial sites (1)

FacilityCityRegionStatus
Al-Azhar university, faculty of medicine, the urology department Cairo Egypt Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06728943 on ClinicalTrials.gov ↗ ← All trials in Egypt