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Clinical Trials in Egypt / NCT06665451
Recruiting Not applicable

Erythropoietin Gel Effect on Dental Implant Stability

NCT06665451 · tracked via the Priya Life Science Egypt tracker
Sponsor
Al-Azhar University
Phase
Not applicable
Started
2025-03-15
Last updated
2026-05-18

Condition(s) studied

Osseointegration

Investigational drug(s) / intervention(s)

Non coated dental implantsErythropoietin gel coated implants

Non coated dental implants: Patients with fresh extraction sockets in the anterior maxilla will be treated by non coated immediate implant .

Erythropoietin gel coated implants: Patients with fresh extraction sockets in the anterior maxilla will be treated by immediate implant coated by erythropoietin gel.

Study summary

* Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants. Numerous coating techniques have been developed to improve and speed up osseointegration.
* The aim of the current study is to assess immediate dental implant stability coated with erythropoietin gel, both clinically and radiographically.
* Materials and Methods: We conducted a randomized controlled clinical trial.The sample will include patients demanding immediate implant treatment in the anterior maxilla . Patients will be randomly allocated into the two groups of the study. The group A will be treated with erythropoietin gel coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . Group B will be treated with non coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla .
* The primary outcome variable will be implant stability and the secondary outcome will be crestal marginal bone level and bone density around implants. It will be measured at time of implant placement and reevaluated after 6-months .

Eligibility

Sex
ALL
Min age
20 Years
Max age
50 Years
Healthy volunteers
Accepted
Inclusion Criteria: * All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement. * Good general periodontal health and maintenance. Exclusion Criteria: * Heavy smokers who smoke more than ten cigarettes per day * Acute infected socket * Ant socket with wall defect. * Pregnency * Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease. * Patients who had subjected to intravenous and/or oral bisphosphonate therapy.

Primary outcome measure(s)

  • Change in implant stability — Baseline and after 6 month
    Implant stability will be assessed by using ( AnyCheck - Implant Stability Tester ) Utilizes physical tapping technique and dumping capacity analysis to measure implant stability with precision

Trial sites (1)

FacilityCityRegionStatus
Faculty of dental medicine Al-Azhar university Asyut Asyut Governorate Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06665451 on ClinicalTrials.gov ↗ ← All trials in Egypt