Clinical Trials in Egypt / NCT05284656
Active, not recruiting
Phase 3
Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease
NCT05284656 · tracked via the Priya Life Science Egypt tracker
Condition(s) studied
Chronic Kidney Diseases
Investigational drug(s) / intervention(s)
combination of Pentoxifylline 400 MG and Folic Acid: drugs used to delay progression of chronic kidney disease
folic acid: drugs used to delay progression of chronic kidney disease
Pentoxifylline 400 MG: drugs used to delay progression of chronic kidney disease
Study summary
The aim of this study is to evaluate the effect of administration of folic acid and /or pentoxifylline on patients with chronic kidney disease (CKD).
Eligibility
Inclusion Criteria:
1. Patients who have chronic kidney disease(CKD) stages 3-5
2. Aged between18 - 60 years old.
3. Both sexes.
4. Stable clinical condition defined as no hospitalizations or cardiovascular events within the 3 months before screening
5. Stable renal function (baseline serum creatinine had to have not increased by 50% in the 3 months before screening)
6. No changes in concomitant medication during the study.
7. Patients who accept to participate in the study.
Exclusion Criteria:
1. Pregnant women
2. Current use of PTF
3. Contraindication to use of PTF drug: history of PTF or theophylline allergy, history of severe retinal hemorrhage or recent cerebral hemorrhage
4. Those with active infections or inflammatory diseases or HIV infection
5. Those with chronic liver disease .
6. Patients who had received immunosuppressive therapy
7. Non-compliant patients
Primary outcome measure(s)
- Change in Serum Creatinine Level — Baseline, 6 months
Change was calculated as the value at 6 months minus the value at baseline.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Al Azhar University | Cairo | Egypt |
More Al-Azhar University trials in Egypt
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05284656 on ClinicalTrials.gov ↗ ← All trials in Egypt