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Clinical Trials in Denmark / NCT07041307
Recruiting Observational

Microvascular Profiling of Nodules in the Thyroid Gland

NCT07041307 · tracked via the Priya Life Science Denmark tracker
Sponsor
Copenhagen University Hospital, Rigshospitalet
Phase
Observational
Started
2025-08-15
Last updated
2025-11-28

Condition(s) studied

Thyroid Nodular Disease

Study summary

The purpose of this study is to examine tiny blood vessels in different thyroid nodules using advanced ultrasound. In the long term, we hope this can help doctors better tell the difference between types of nodules and more accurately decide who may need surgery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Age over 18 years * Written and verbal informed consent to participate in the study * Patients with hypo-, iso-, or hyperfunctioning thyroid nodules * Patients referred for thyroid surgery due to suspected malignant nodule (including Bethesda classification groups III, IV, V, and VI) * Healthy volunteers - generally good health with no chronic illnesses Exclusion Criteria: * Pregnancy * Inability to undergo the examination due to physical or mental limitations * Desire to opt out of receiving information about new, significant health findings revealed during the study * Healthy Participants: * Thyroid disease, including nodules, as well as current or past conditions affecting the thyroid * Medication that affects thyroid function

Primary outcome measure(s)

  • Visualization of the Microvasculature in the Thyroid Gland and Thyroid Nodules — 30 minutes
    With super-resolution ultrasound imaging using the erythrocytes, the investigators will visualize the microvasculature in normal thyroid tissue and different types of thyroid nodules.

Trial sites (2)

FacilityCityRegionStatus
Rigshospitalet Copenhagen Denmark Recruiting
Technical University of Denmark Lyngby Denmark Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07041307 on ClinicalTrials.gov ↗ ← All trials in Denmark