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Clinical Trials in Denmark / NCT06654986
Recruiting Not applicable

Muscle Anabolic Response to β2-adrenergic Stimulation With Increased Amino Acid Availability.

NCT06654986 · tracked via the Priya Life Science Denmark tracker
Sponsor
University of Copenhagen
Phase
Not applicable
Started
2024-10-31
Last updated
2025-04-09

Condition(s) studied

Healthy

Investigational drug(s) / intervention(s)

Salmeterol + amino acid availability →Salmeterol + placeboPlacebo + placebo

Salmeterol + amino acid availability: The participants will be administered 200 µg salmeterol (8 puffs) from a MDI device and 40 g amino acid availability (clear whey in a shaker with water) daily during a 6-week intervention. Participants will be instructed to provide documentation of both the inhalation and the shaker intake via video.

Salmeterol + placebo: The participants will be administered 200 µg salmeterol (8 puffs) from a MDI device. Furthermore they will be administered 80 g placebo (carbo fuel in a shaker with water) daily during a 6-week intervention. Participants will be instructed to provide documentation of both the inhalation and the shaker intake via video.

Placebo + placebo: The participants will be administered placebo (8 puffs) from a MDI device. Furthermore they will be administered 80 g placebo (carbo fuel in a shaker with water) daily during a 6-week intervention. Participants will be instructed to provide documentation of both the inhalation and the shaker intake via video.

Study summary

The purpose of the project is to investigate the effect of amino acid availability on the muscle anabolic response to beta2-adrenergic stimulation in young healthy men and women.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Age 18-40 * Physically active \>5 hours a week * Maximum oxygen uptake classified as high or very high Exclusion Criteria: * Active smoker currently or within the past 5 years * Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women) * Chronic or acute illness deemed by the responsible study physician to affect the test parameters * Deviation from the study protocol * Lean mass index \>21 kg/m² * Pregnancy * Smoker * Blood donation during the past 3 months

Primary outcome measure(s)

  • Skeletal muscle hypertrophy — Through study completion, an average on 7 weeks
    Muscle hypertrophy measured using Dual-energy X-ray Absorptiometry (DXA).

Trial sites (1)

FacilityCityRegionStatus
August Krogh Building Copenhagen Denmark Recruiting

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POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS Recruiting
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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06654986 on ClinicalTrials.gov ↗ ← All trials in Denmark