Prehospital ECPR in Moravia Silesia Region

Condition(s) studied

Investigational drug(s) / intervention(s)

Extracorporeal membrane oxygenation (ECMO): In extracorporeal membrane oxygenation (ECMO), blood is pumped outside of the body to a heart-lung machine. The machine removes carbon dioxide and sends oxygen-rich blood back to the body. Blood flows from the right side of the heart to the heart-lung machine. It's then rewarmed and sent back to the body.

Study summary

Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) in specific cases could be improved by Extracorporeal membrane oxygenation (ECMO; ECPR). ECPR could be introduced in hospital after retrieval of an OHCA patient and also faster by implantation on scene. The aim is to verify the effectiveness of ECPR on scene in the Moravian-Silesian region.

Eligibility

Primary outcome measure(s)

• Time from cardiac arrest (collapse) to implantation of ECMO — up to 60 minutes
  The time from cardiac arrest (collapse) to implantation of ECMO will be recorded and assessed
• Hospital mortality — up to 3 weeks
  Hospital mortality will be assessed for the period of 3 weeks
• Cerebral Performance Category (CPC) score — 30 days
  Cerebral Performance Category (CPC) score will be observed 30 days after cardiac arrest
• Neurological outcome (CPC score) — 6 months
  Neurological outcome will be assessed using the Cerebral Performance Category Scale (CPC) 6 months after cardiac arrest.
• Neurological outcome (SF-36) — 6 months
  Neurological outcome will be assessed using the Short Form 36 Health Subject Questionnaire (SF-36) 6 months after cardiac arrest.
• Neurological outcome (EQ-5D) — 6 months
  Neurological outcome will be assessed using the European Quality of Life Questionnaire (EQ-5D) 6 months after cardiac arrest.

Trial sites (2)

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