Multimodal CT Examination in Stroke Mimics Diagnosis

NCT06045455 · tracked via the Priya Life Science Czechia tracker

Sponsor

University Hospital Ostrava

Phase

Observational

Started

2023-10-01

Last updated

2024-01-16

Condition(s) studied

Stroke Mimics

Investigational drug(s) / intervention(s)

Multimodal brain CTMagnetic resonance imaging (MRI)

Multimodal brain CT: Multimodal brain CT includes NCCT, CTP, and CTA

Magnetic resonance imaging (MRI): MRI examination will be performed between the 3rd and 7th day after the admission to the hospital

Study summary

The proposed project is a multicentre prospective observational clinical research focused on refining multimodal computer tomography (CT) diagnostics in stroke mimics. The main aim is to accurately identify SM in order to minimize the risk of receiving inappropriate treatment and possible development of complications, which can have a negative impact on the patient´s health. The project includes an analysis of pharmacoeconomic parameters. It will examine saved costs in the case of non-administration of unindicated treatment and it will compare the number of adverse events related to the administration of unindicated treatment in patients diagnosed with SM.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: \- an acute focal neurological deficit (minimum 1 point on the National Institutes of Health Stroke Scale - NIHSS) within 24 hours from the onset of symptoms Exclusion Criteria: * the last period of normality is unknown prior to multimodal CT examination * the last period of normality is \>24 hours prior to multimodal CT examination * the diagnostic evaluation is incomplete * a final neurologic diagnosis cannot be determined

Primary outcome measure(s)

The difference of patients with SM — up to 7 days
The primary objective is to demonstrate the specificity and sensitivity of multimodal brain imaging (NCCT, CTA and CTP) when compared to the use of NCCT or NCCT/CTA in the acute diagnostics of SM in patients with a sudden focal neurological deficit (minimum 1 point on the National Institutes of Health Stroke Scale - NIHSS) within 24 hours from the onset of symptoms. The difference will be measured in per cent (%)

Trial sites (3)

Facility	City	Region	Status
University of Ostrava	Ostrava	Moravian-Silesian Region	Recruiting
University Hospital Ostrava	Ostrava	Moravian-Silesian Region	Recruiting
Hospital České Budějovice	České Budějovice	South Bohemian Region	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06045455 on ClinicalTrials.gov ↗ ← All trials in Czechia