A Study of Zovaglutide (ZT002 Injection) in Participants With Hepatic Impairment and Healthy Participants
Condition(s) studied
Investigational drug(s) / intervention(s)
Zovaglutide: All subjects will be treated with a single subcutaneous injection of Zovaglutide
Zovaglutide: All subjects will be treated with a single subcutaneous injection of Zovaglutide
Zovaglutide: All subjects will be treated with a single subcutaneous injection of Zovaglutide.
Study summary
This study is a single-dose, open-label, non-randomized, parallel design phase I clinical study to evaluate the PK characteristics and safety of single subcutaneous injection of ZT002 Injection in participants with varying degrees of Hepatic Impairment and matched participants with normal hepatic function.
Eligibility
Primary outcome measure(s)
- Area Under the Concentration Versus Time Curve (AUC) of ZT002 From Time Zero to Infinity (AUC0-∞) — Start of treatment up to Day 36
- Maximum Concentration of ZT002 (Cmax) — Start of treatment up to Day 36
- Area Under the Concentration Versus Time Curve (AUC) of ZT002 From Time Zero to Tlast (AUC0-t) — Start of treatment up to Day 36
Trial sites (3)
| Facility | City | Region | Status |
|---|---|---|---|
| The Second Affiliated Hospital of Chongqing Medical University | Chongqing | Chongqing Municipality | |
| Henan Infectious Diseases Hospital & The Sixth People's Hospital of Zhengzhou | Zhengzhou | Henan | |
| Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital | Chengdu | Sichuan |
More Beijing QL Biopharmaceutical Co.,Ltd trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07916194 on ClinicalTrials.gov ↗ ← All trials in China