Study on the Impact of Different Feeding Methods on Allergy Prevention and Digestive Absorption in Infants and Young Children

Condition(s) studied

Investigational drug(s) / intervention(s)

Observation: Collect questionnaire information.

biological sample collection: stool: Collect the stool sample from selected participants under standard instruction

Study summary

Based on a real-world research paradigm, this study aims to evaluate the performance of infants fed via different methods-specifically goat milk formula, control formula, and breastfeeding-regarding allergy prevention and protein digestion and absorption. The study begins with a cross-sectional survey to compare differences among these groups in terms of allergy-related markers, stool characteristics, and feeding difficulties. Subsequently, a prospective follow-up cohort study will be conducted based on these real-world feeding groups to monitor the incidence of allergies and other related data; stool samples will also be collected to analyze markers associated with protein digestion.

Eligibility

Primary outcome measure(s)

• Rates of infant allergy, respiratory disease, digestive disease occurrence in each group — Enrollment and 3 follow-up time points
  Rates of disease using percentage(%) of affected population/ whole population in each group.
• The Montreal Children's Hospital Feeding Scale, MCH-FS — Enrollment and 3 follow-up time points
  The Montreal Children's Hospital Feeding Scale (MCH-Feeding Scale) consists of 14 items with each item scoring 1-7, the overall score range would be 14-98, higher score indicates poorer feeding performance.
• 16s RNA gut microbiota — Enrollment and 3 follow-up time points

Trial sites (1)

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