Ireland
--:--IST
Recruiting Observational

Innate Immune Cell Phenotypes and Early Fibrotic Repair in Acute Myocardial Infarction

NCT07764588 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2026-01-01
Last updated
2026-08-14

Condition(s) studied

Myocardial Infarction

Study summary

To determine the relationship of the phenotypes of neutrophils and monocytes with early fibrotic repair after acute myocardial infarction.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: \---- Age \> 18 and ≤ 80 years old \- Patients with acute STEMI within 12 hours of symptom onset who are planned to receive PPCI Exclusion Criteria: * Prior revascularization * Known allergy to gadopentetate dimeglumine contrast agent * Pregnancy or planned pregnancy within the next 6 months * Life expectancy \< 1 year * Metallic implants or claustrophobia that precluded MRI * Severe COPD or inability to hold breath for MRI * Severe hepatic or renal dysfunction (ALT \> 5×ULN or eGFR \< 15 mL/min/1.73 m²)

Primary outcome measure(s)

  • Major cardiac adverse outcome — At 12 months after enrollment
    The composite endpoint included cardiac death, non-fatal myocardial infarction, and rehospitalization for angina.

Trial sites (1)

FacilityCityRegionStatus
Shanghai Tenth People's Hospital Shanghai China Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07764588 on ClinicalTrials.gov ↗ ← All trials in China