Vascular Aging and Acute Kidney Injury After Cardiac Surgery

Condition(s) studied

Investigational drug(s) / intervention(s)

Multidimensional Vascular Aging Assessment: Perioperative assessment of vascular aging-related indicators, including noninvasive vascular assessments, hemodynamic measurements, and relevant clinical and laboratory variables. The assessment is observational and will not determine the treatment, surgical procedure, or perioperative management assigned to participants.

Study summary

This prospective observational cohort study will enroll adult patients undergoing cardiac surgery at Nanjing First Hospital, Nanjing Medical University. The study will evaluate multidimensional vascular aging markers before surgery and assess their association with postoperative acute kidney injury within 7 days after surgery. No intervention will be assigned by the study protocol, and all perioperative management will follow routine clinical practice.

Eligibility

Primary outcome measure(s)

• Incidence of Postoperative Acute Kidney Injury Within 7 Days After Surgery — From the date of surgery to postoperative day 7
  Postoperative acute kidney injury will be assessed within 7 days after surgery according to predefined diagnostic criteria based on postoperative renal function changes. The outcome will be recorded as the occurrence of acute kidney injury during the postoperative 7-day period.

Trial sites (1)

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