Ireland
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Recruiting Observational

A Prospective Study on the Diagnosis of Malignant Tumors With 18F-FGIn PET/CT

NCT07602569 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2025-10-20
Last updated
2026-05-22

Condition(s) studied

Cancer (With or Without Metastasis)

Study summary

Glutamine is a crucial nutrient for cancer cell growth, and its metabolism is frequently dysregulated in malignancies. 18F-FGln is a PET tracer that targets this altered glutamine metabolism. However, there are currently limited studies on the diagnostic value of 18F-FGln PET/CT in various types of cancer. Therefore, this prospective study was conducted to investigate the value of 18F-FGln PET/CT in patients with various types of malignant tumors.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: 1. Patients with clinical suspicion or exclusion of primary or recurrent malignant tumors (such as glioma of the brain, liver cancer, gastric cancer, duodenal cancer, colorectal cancer, ovarian cancer, etc., where 18F-FDG is prone to false negatives and false positives) 2. Patients undergoing tumor staging or evaluating treatment effect using 18F-FDG PET/CT or 18F-FGln PET/CT to determine the most appropriate treatment strategy 3. Patients without other tumor history 4. Patients with good compliance, providing informed consent, and able to follow the research protocol Exclusion Criteria: 1. pregnant or lactating patients or patients under 18 years old 2. the subjects and their parents or legal representatives are unable or unwilling to provide written informed consent; 3. patients with poor compliance, unable to tolerate or cooperate with PET/CT examinations. 4. those who have undergone gastrointestinal barium meal examination within one week; 5. other situations where the investigators consider it inappropriate for the subjects to participate in this clinical trial

Primary outcome measure(s)

  • SUVMAX — Within one day after the PET/CT scan
    Xingxiang's Chinese report system automatically delineates the areas of interest.
  • TBR — Within one day after the PET/CT scan
    Xingxiang's Chinese report system automatically delineates the areas of interest.

Trial sites (1)

FacilityCityRegionStatus
Affiliated Cancer Hospital & Institute of Guangzhou Medical University Guangzhou China Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07602569 on ClinicalTrials.gov ↗ ← All trials in China