Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery

NCT07598019 · tracked via the Priya Life Science China tracker

Sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Phase

Observational

Started

2026-06-15

Last updated

2026-05-20

Condition(s) studied

Neurocognitive DisorderCardiac Surgery

Study summary

The goal of this observational study is to explore the effect of remimazolam-based total intravenous anesthesia on postoperative neurocognitive function in patients who undergo cardiovascular surgery.

The main question this study tries to answer is: Does remimazolam influence the incidence of postoperative delirium in cardiovascular surgery? Participants already apply remimazolam-based total intravenous anesthesia as part of their regular medical treatment for general anesthesia to perform cardiac surgery will answer questionnaires about cognitive function after surgery.

Eligibility

Sex

ALL

Min age

60 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. Male or female adult patients aged 60 years or older 2. Receiving elective cardiovascular surgery with cardiopulmonary bypass 3. Written Informed consent provided Exclusion Criteria: 1. Deep hypothermia circulatory arrest 2. Breastfeeding or pregnancy 3. Mental or legal disability 4. Terminal illness with a life expectancy of less than 3 months 5. Unable to receive neuro-cognitive evaluation due to language, vision, or hearing impairments

Primary outcome measure(s)

the 5-day incidence of postoperative delirium — within five days postoperatively
the incedence of delirium evaluated by CAM/CAM-ICU

Trial sites (1)

Facility	City	Region	Status
State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College	Beijing	Beijing Municipality

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07598019 on ClinicalTrials.gov ↗ ← All trials in China