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Recruiting Observational

Association Between Microplastic Exposure and the Pathological Progression of Gastric Carcinogenesis

NCT07542652 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2026-03-31
Last updated
2026-04-30

Condition(s) studied

Gastric CarcinomaGastritis ChronicIntestinal MetaplasiaGastric Precancerous Lesions

Study summary

The objective of this clinical trial is to explore the correlation between the level of microplastic exposure and the risk of gastric mucosal carcinogenesis, and to evaluate the strength of its effect as an independent risk factor. The main questions it aims to answer include: Does the level of microplastic exposure increase the risk of gastric mucosal carcinogenesis? Can the correlation between the level of microplastic exposure and gastric mucosal carcinogenesis, as well as the sources of high - risk microplastic exposure, be explored through a questionnaire on external microplastic exposure? Researchers will complete a design structured questionnaire and ask participants to fill it out carefully and truthfully to determine whether the level of microplastic exposure increases the risk of gastric mucosal carcinogenesis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Aged between 18 and 75 years old, gender is not restricted * Having a clear diagnosis result within the recent three months and being diagnosed with chronic non - atrophic gastritis, precancerous lesions of gastric cancer, or gastric cancer for the first time * Have clear Helicobacter pylori (Hp) test results * Be in normal mental state and able to independently complete the questionnaire survey Exclusion Criteria: * Patients with a history of malignant tumors in other parts * Patients who have previously undergone upper gastrointestinal surgery, chemotherapy, or radiotherapy * Patients with severe diseases of major organs such as the heart, lungs liver, and kidneys * Patients who are currently receiving psychological intervention or taking psychiatric drugs * Pregnant or lactating women * Patients with severe missing clinical data or questionnaire information * Refusing to sign the informed consent form

Primary outcome measure(s)

  • Correlation between external exposure levels of microplastics and three pathological stages of gastric mucosal carcinogenesis — 9 months
    The investigators evaluated the correlation between external exposure to microplastics and the three pathological stages of gastric mucosal carcinogenesis based on the patients' final diagnosis results and the completed questionnaires they filled out.

Trial sites (1)

FacilityCityRegionStatus
Xijing Hosipital of Digestive Disease Xi'an Shaanxi Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07542652 on ClinicalTrials.gov ↗ ← All trials in China