Ireland
--:--IST
Enrolling by invitation Observational

Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?

NCT07494006 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2025-07-15
Last updated
2026-03-27

Condition(s) studied

Lung CancerOLVHypoxemia During Surgery

Study summary

Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breathing and intraoperatively record the lowest peripheral oxygen saturation (SpO₂) during OLV. The aim is to investigate the correlation between these two parameters. The findings are expected to facilitate the prediction of hypoxemia in thoracic surgical patients undergoing OLV.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age ≥ 18 years * BMI \> 18.5 and \< 30 * Informed consent obtained Exclusion Criteria: * • Inability to use the EIT belt preoperatively * Failure to implement one-lung ventilation during surgery

Primary outcome measure(s)

  • Lowest SpO₂ during OLV — Perioperative
    We will record the value of the lowest peripheral oxygen saturation (SpO₂) during intraoperative one-lung ventilation.

Trial sites (1)

FacilityCityRegionStatus
Peking University People's Hospital Beijing China
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07494006 on ClinicalTrials.gov ↗ ← All trials in China