A Study of IMV102 in Patients With Relapsed/Refractory Multiple Myeloma
Condition(s) studied
Investigational drug(s) / intervention(s)
IMV102 treatment: Eligible patients with relapsed/refractory multiple myeloma will receive an infusion of IMV102 injection, and the safety and efficacy of IMV102 injection will be evaluated within 24 months post-infusion.
Study summary
This is an investigator-initiated, single-center, early-phase clinical study comprising dose escalation and dose expansion phases, designed to evaluate the safety and efficacy of IMV102 in subjects with relapsed/refractory multiple myeloma (RRMM). Eligible subjects will receive an infusion of IMV102 injection. Blood and urine samples will be collected before and after infusion for pharmacokinetic, pharmacodynamic, immunogenicity, and safety assessments.
Tumor response will be evaluated according to the International Myeloma Working Group (IMWG) uniform response criteria (2016). Assessments will be performed at baseline, and then at Day 28 post-infusion, Month 2, Month 3, and subsequently every 3 months from Month 3 to Month 24, until the subject completes the 24-month follow-up period, experiences disease progression (PD)/relapse, initiates new anti-tumor therapy, dies, or withdraws from the study, whichever occurs first.
Eligibility
Primary outcome measure(s)
- To evaluate the safety of IMV102 injection in patients with relapsed/refractory multiple myeloma — 24 months post IMV102 infusion
Incidence of adverse events and its severity after IMV102 injection treatment
Trial sites (4)
| Facility | City | Region | Status |
|---|---|---|---|
| Beijing GoBroad Boren Hospital | Beijing | China | Recruiting |
| The second affiliated hospital of Chongqing medical university | Chongqing | China | Not Yet Recruiting |
| Renji Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai | China | Not Yet Recruiting |
| Zhengzhou Yihe Hospital | Zhengzhou | China | Not Yet Recruiting |
More Suzhou Immunofoco Biotechnology Co., Ltd trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07493135 on ClinicalTrials.gov ↗ ← All trials in China