Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and Cytology Whole-Slide Images

NCT07488325 · tracked via the Priya Life Science China tracker

Sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Phase

Observational

Started

2026-03-01

Last updated

2026-04-01

Condition(s) studied

Thyroid Nodule

Investigational drug(s) / intervention(s)

Histopathology or cytopathology.

Histopathology or cytopathology.: This is a observation stufy.

Study summary

The prospective study aim to develop a multimodal deep learning model that integrates ultrasound images and cytological whole-slide images for more accurate malignant risk prediction of Bethesda III thyroid nodules.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: * (a) Patients who underwent fine-needle aspiration of thyroid nodules and received a cytological diagnosis of Bethesda Ⅲ. * (b) Patients who subsequently underwent thyroid surgery with a definitive histopathological diagnosis of benign or malignant lesions,. * (c) Availability of at least one ultrasound image acquired prior to surgery. Exclusion Criteria: * (a) Patients without confirmation by surgical pathology,. * (b) Patients without any available or usable ultrasound images.

Primary outcome measure(s)

Pathological diagnosis. — One month after the surgery.
WHO guidelines.

Trial sites (1)

Facility	City	Region	Status
No. 33 Yingfeng Road, Haizhu District, Guangzhou City, Guangdong Province, Sun Yat-sen Memorial Hospital	Guangzhou	Guangzhou	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07488325 on ClinicalTrials.gov ↗ ← All trials in China