A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo
Condition(s) studied
Investigational drug(s) / intervention(s)
GIA632: GIA632 will be administered during the 48-week core period.
Placebo: Placebo will be administered during the 48-week core period.
Study summary
The main purpose of this multicenter, randomized, double-blind, placebo-controlled Phase 2b study is to investigate the safety and efficacy of GIA632 in participants with NSV and to identify the optimal dose to be promoted into the confirmatory Phase 3 program.
Eligibility
Primary outcome measure(s)
- Percentage change from baseline in Facial Vitiligo Area Scoring Index (F-VASI) score. — Baseline, Week 24
The F-VASI assesses the percentage of facial area affected by vitiligo. It ranges from 0 to 3.5, with 0 representing no vitiligo on the face and 3.5 representing complete depigmentation of the assessed facial areas.
Trial sites (83)
| Facility | City | Region | Status |
|---|---|---|---|
| Cahaba Derm and skin hlth ctr 27 | Birmingham | Alabama | Recruiting |
| First OC Dermatology | Fountain Valley | California | Recruiting |
| MedDerm Associates | San Diego | California | Recruiting |
| Clinical Trials Research Institute | Thousand Oaks | California | Recruiting |
| Encore Medical Research | Hollywood | Florida | Recruiting |
| Mayo Clinic Jacksonville | Jacksonville | Florida | Recruiting |
| Miami Derm and Laser Institute | Miami | Florida | Recruiting |
| Global Clinical Professionals | St. Petersburg | Florida | Recruiting |
| Endeavor Health | Glenview | Illinois | Recruiting |
| Dawes Fretzin Clinical Rea Group | Indianapolis | Indiana | Recruiting |
| DermAssociates LLC | Rockville | Maryland | Recruiting |
| Uni Of Michigan Health System | Ann Arbor | Michigan | Recruiting |
| Hamzavi Dermatology | Fort Gratiot | Michigan | Recruiting |
| Revival Research Institute | Troy | Michigan | Recruiting |
| Skin Specialists PC | Omaha | Nebraska | Recruiting |
| Las Vegas Dermatology | Las Vegas | Nevada | Recruiting |
| Equity Medical | The Bronx | New York | Recruiting |
| Oregon Medical Research Center | Portland | Oregon | Recruiting |
| International Clinical Research Tennessee LCC | Murfreesboro | Tennessee | Recruiting |
| Bellaire Dermatology Associates | Bellaire | Texas | Recruiting |
| Center for Clinical Studies | Houston | Texas | Recruiting |
| Austin Inst for Clinical Research | Pflugerville | Texas | Recruiting |
| ACRC Trials | Plano | Texas | Recruiting |
| Virginia Clinical Research | Norfolk | Virginia | Recruiting |
| Novartis Investigative Site | Buenos Aires | Buenos Aires | Recruiting |
| Novartis Investigative Site | Caba | Buenos Aires | Recruiting |
| Novartis Investigative Site | Rosario | Santa Fe Province | Recruiting |
| Novartis Investigative Site | Caba | Argentina | Recruiting |
| Novartis Investigative Site | San Miguel de Tucumán | Argentina | Recruiting |
| Novartis Investigative Site | Sydney | New South Wales | Recruiting |
| Novartis Investigative Site | Waitara | New South Wales | Recruiting |
| Novartis Investigative Site | Melbourne | Victoria | Recruiting |
| Novartis Investigative Site | Calgary | Alberta | Recruiting |
| Novartis Investigative Site | Winnipeg | Manitoba | Recruiting |
| Novartis Investigative Site | Mississauga | Ontario | Recruiting |
| Novartis Investigative Site | Newmarket | Ontario | Recruiting |
| Novartis Investigative Site | Toronto | Ontario | Recruiting |
| Novartis Investigative Site | Québec | Quebec | Recruiting |
| Novartis Investigative Site | Guangzhou | Guangdong | Recruiting |
| Novartis Investigative Site | Wuhan | Hubei | Recruiting |
+ 43 more sites — see the full list on the official registry below.
More Novartis Pharmaceuticals trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07431177 on ClinicalTrials.gov ↗ ← All trials in China