Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy

Condition(s) studied

Investigational drug(s) / intervention(s)

Non-invasive Eye Tracking Assessment: This is an observational study; no therapeutic intervention is administered. All participants undergo a single, standardized study visit that includes: Participants will undergo a visual function assessment using a desktop-based high-frequency eye tracker. The assessment consists of three parts: 1. Calibration: To ensure accurate gaze tracking. 2. Oculomotor Tasks: Participants track visual targets to measure fixation stability and smooth pursuit capabilities. 3. Visual Attention Tasks: Participants view static images to record scanning patterns. The entire process is non-invasive and lasts approximately 15-20 minutes.

Study summary

This study focuses on eye health and visual function in patients with Thyroid-Associated Ophthalmopathy (TAO), a condition that often causes bulging eyes and restricted eye movement. The purpose of this study is to use non-invasive eye-tracking technology to evaluate how the disease affects eye movement function. The investigators hypothesize that compared to healthy individuals, patients with TAO will show measurable differences in eye stability and the ability to track moving objects. Additionally, the investigators believe the disease may alter how patients visually scan faces (e.g., avoiding eye contact). The study will enroll 100 participants, including both patients and healthy volunteers. By recording gaze patterns while participants look at a screen, the investigators aim to objectively quantify the physical and social impact of the disease, providing better data for future treatment plans.

Eligibility

Primary outcome measure(s)

• Smooth Pursuit Function Gaze Distribution — Baseline
  Participants track a moving target on the screen. This metric quantifies the spatial distribution of fixation points recorded throughout the task duration

Trial sites (1)

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