Ireland
--:--IST
Recruiting Observational

Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke

NCT07294274 · tracked via the Priya Life Science China tracker
Sponsor
Phase
Observational
Started
2025-11-01
Last updated
2026-02-05

Condition(s) studied

Post-stroke Depression

Investigational drug(s) / intervention(s)

Group patients based on whether they have been diagnosed with PSD.

Group patients based on whether they have been diagnosed with PSD.: Group patients based on whether they have been diagnosed with PSD.

Study summary

Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive impairments, greater economic burdens, and lower quality of life, but also brings additional medical expenses and care pressure to families. Society also needs to bear higher medical costs. Currently, the early diagnosis of PSD is difficult, which may lead to poor prognosis after stroke. This study aims to utilize machine learning technology to integrate multi-dimensional indicators of patients with ischemic stroke, establish a risk prediction model for PSD, and assist in early, accurate, and individualized assessment of PSD risk in clinical practice.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients with acute ischemic stroke; * Admission within 7 days of symptom onset; * The patient and/or the family members sign a written informed consent form. Exclusion Criteria: * Confusion of consciousness,severe cognitive impairment, etc * Individuals with a history of depression, schizophrenia, bipolar disorder, etc; * Individuals unable to participate in neuropsychological examinations due to hearing im pairments, lack of coordination, or neurological deficits, including se vere aphasia.

Primary outcome measure(s)

  • The number of post-stroke depression (PSD) that occurs 3 months after stroke — 3 months after stroke

Trial sites (1)

FacilityCityRegionStatus
The First Affiliated Hospital of Chongqing Medical University Chongqing China Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07294274 on ClinicalTrials.gov ↗ ← All trials in China