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Recruiting Observational

AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population

NCT07277686 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2025-12-11
Last updated
2026-01-06

Condition(s) studied

Coronary Artery Disease (CAD)Artificial Intelligence AlgorithmsFaceScreening

Investigational drug(s) / intervention(s)

No Intervention

No Intervention: No Intervention

Study summary

This study aims to evaluate the effectiveness of this facial image-based AI algorithm for screening CAD in high-risk community populations (specifically individuals with diabetes, hypertension, or aged over 65). The main objectives are:

1. To verify if the AI algorithm can accurately distinguish between high-risk and low-risk groups by comparing the actual prevalence of CAD in these groups.
2. To compare the CAD detection rate using this AI screening strategy against the natural detection rate in a real-world cohort.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Age \>= 18 years. * Community high-risk population, defined as individuals meeting at least one of the following criteria: 1. Diagnosed with Diabetes Mellitus; 2. Diagnosed with Hypertension; 3. Advanced age (\> 65 years old). Exclusion Criteria: * Prior confirmed diagnosis of Coronary Heart Disease (CAD), including clinically diagnosed CAD, history of Coronary Artery Bypass Grafting (CABG), or history of Percutaneous Coronary Intervention (PCI). * History of diagnosed Heart Failure. * Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup. * Refusal to participate in the study.

Primary outcome measure(s)

  • Difference in Prevalence of CAD Between AI-Stratified High-Risk and Low-Risk Groups — Up to 6 months
    Participants in the diagnostic test cohort are stratified into high-risk and low-risk groups using the AI screening strategy. Subsequently, all participants undergo Coronary Computed Tomography Angiography (CCTA). This outcome measures the difference in CAD prevalence between the two groups based on CCTA results.

Trial sites (3)

FacilityCityRegionStatus
Zhoukou Chuanhui District Hospital of Traditional Chinese Medicine Zhoukou Henan Recruiting
Zhoukou Specialized Disease Hospital Zhoukou Henan Recruiting
Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Not Yet Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07277686 on ClinicalTrials.gov ↗ ← All trials in China