Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact
Recruiting Phase 1/2

Exploratory Study of Super DC Cell Injection in Preventing Recurrence After Radical Surgery for Tumors

NCT07146672 · tracked via the Priya Life Science China tracker
Phase
Phase 1/2
Started
2025-07-31
Last updated
2025-08-28

Condition(s) studied

Solid Tumor Cancer

Investigational drug(s) / intervention(s)

Super DC Vaccine

Super DC Vaccine: Super DC Cell Injection

Study summary

The study is a controlled, open-label exploratory clinical trial.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-80 years old, weight ≥ 40kg; No gender limit; * Subjects with malignant solid tumors diagnosed by histology or cytology and undergoing radical resection surger; * At the beginning of the study (after surgery), there were no lesions, no local recurrence or distant metastasis on the imaging, and no brain metastasis (images within one month before enrollment can be used for screening); * Subjects in the safety verification stage need to provide immunohistochemical test results with positive expression of Survivin or P53 or MUC1; * ECOG score 0-1 points; * There are sufficient venous channels and no contraindications for peripheral blood mononuclear cell collection surgery; * Organs and bone marrow function well: * a:Cardiac function: Left ventricular ejection fraction (LVEF) ≥ 50% evaluated by echocardiography within one month of enrollment; The electrocardiogram is basically normal; * b:Platelets ≥ 90 × 10 \^ 9/L; * c:Hemoglobin ≥ 90g/L (no blood transfusion or erythropoietin dependence within 7 days); * d:Total bilirubin ≤ 2 times the upper limit of normal value; * e:Serum creatinine ≤ 1.5 times the upper limit of normal value; * f:Transaminases (AST, ALT) ≤ 2.5 times the upper limit of normal value (if liver cancer is 5 times the upper limit of normal value); * g:International standardized ratio (INR) or prothrombin time (PT) ≤ 1.5 times the upper limit of normal value; * Able to understand trial requirements and matters, willing to participate in clinical research according to trial requirements Exclusion Criteria: * Positive for HIV antibodies or syphilis antibodies; positive for hepatitis B surface antigen, and positive for hepatitis B core antibody or e antibody with viral DNA copy number above the detection limit or ≥1000 copies/ml; or hepatitis C virus RNA copy number above the detection limit. * Any uncontrollable active infection, coagulation disorder, or any other major disease; * Pregnant or lactating women; * Suffering from active neuroautoimmune or inflammatory diseases, such as any of the following: inflammatory bowel disease, systemic lupus erythematosus, ankylosing spondylitis, scleroderma, multiple sclerosis, Sjogren's syndrome, etc., and receiving relevant treatment; Subjects who are still using immunosuppressants for organ transplantation; Or subjects who have been using immunosuppressive drugs such as glucocorticoids for a long time cannot stop at least 4 weeks before enrollment; Severe allergic constitution; * Subjects with existing abnormalities in the central nervous system, such as seizures, cerebral vascular ischemia/bleeding, dementia, cerebellar diseases, or any autoimmune diseases associated with central nervous system involvement; * Major cardiovascular diseases with clinical significance include:

Primary outcome measure(s)

  • Dose-limiting toxicity — Within 28 days after the first injection
    Safety

Trial sites (1)

FacilityCityRegionStatus
Shanghai Mengchao Tumor Hospital Shanghai China Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07146672 on ClinicalTrials.gov ↗ ← All trials in China