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Clinical Trials in China / NCT07009067
Recruiting Not applicable

Safety and Efficacy of Exercise in Type-B Aortic Dissection

NCT07009067 · tracked via the Priya Life Science China tracker
Sponsor
Guangdong Provincial People's Hospital
Phase
Not applicable
Started
2025-05-06
Last updated
2025-06-06

Condition(s) studied

Type B Aortic Dissection

Investigational drug(s) / intervention(s)

Exercise-based Cardiac Rehabilitation

Exercise-based Cardiac Rehabilitation: Participated will receive 36 individualized Exercise-based Cardiac Rehabilitation after enrollment in our Cardiac Rehabilitation Center.

Study summary

This is a pilot study. The goal of this clinical trial is to evaluate the safety and efficacy of exercise-based cardiac rehabilitation in patients with Type-B Aortic dissection or intramural hematoma or penetrating ulcer and received endovascular repair. The main questions it aims to answer are:

• Is exercise-based cardiac rehabilitation safe among these patients? Participants will be randomly assigned to receive usual care plus exercise-based cardiac rehabilitation (guided exercise for 3 months in rehabilitation center) or usual care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Patients with a previous diagnosis of type B aortic dissection or intramural hematoma or penetrating ulcer, who underwent endovascular aortic repair (EVAR) or EVAR + supra-aortic shunt surgery for more than 1 month, and no related complications (such as endoleak, stent thrombosis, dissection progression, etc.) were found in the postoperative aortic CTA; * Able to independently carry out basic daily life activities, participants must be able to complete the baseline assessment and start the designated treatment; * Patients voluntarily participate in this study, sign the written informed consent, and are willing to cooperate with the follow-up; Exclusion Criteria: * Acute myocardial infarction occurred 1 month ago; * Combined with severe aortic stenosis or regurgitation; * Combined with ascending aortic aneurysm or dissection; * Acute heart failure occurred 2 weeks ago; * Combined with severe hypertrophic obstructive cardiomyopathy; * Chronic renal failure stage 5, which is defined as glomerular filtration rate \<15ml/(min·1.73m2) or dialysis; * During the screening examination, the patient's alanine aminotransferase or aspartate aminotransferase is greater than or equal to 5 times the upper limit of the normal value specified by our center; * Patients with any medical history that may affect compliance with the program; * Patients with severe language, mental or physical disabilities who are unable to participate in the program; * Pregnant or lactating women, or those with fertility who are unwilling/unable to take effective contraceptive measures; * Patients participating in other interventional clinical trials; * Patients with long-term high-intensity exercise habits; * Patients who are judged by the researchers to be unsuitable for participation in this study;

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Guangdong Provincial People's Hospital Guangzhou Guangdong Recruiting

More Guangdong Provincial People's Hospital trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07009067 on ClinicalTrials.gov ↗ ← All trials in China