Community-Empowerment and Environmental Enrichment-based Co-management (CEEEC) Model and Mechanisms for Improving Health of Older Stroke Patients With Multimorbidity

NCT06975501 · tracked via the Priya Life Science China tracker

Sponsor

Duke Kunshan University

Phase

Not applicable

Started

2025-06-20

Last updated

2026-10-29

Condition(s) studied

HypertensionType 2 Diabetes Mellitus (T2DM)MultimorbidityStroke

Investigational drug(s) / intervention(s)

Exercise InterventionCognitive Intervention

Exercise Intervention: Participants will receive twice-weekly aerobic and balance training sessions, with medication compliance education.

Cognitive Intervention: Participants will participate in twice-weekly structured cognitive training sessions, with medication compliance education.

Study summary

This study is a cluster randomized controlled trial with a 2×2 factorial design conducted in community health centers in Kunshan, Wuhan and Shanghai, China. It aims to evaluate the independent and combined effects of exercise and cognitive interventions on intrinsic capacity and related health outcomes among stroke survivors aged 60 years and older with hypertension or type 2 diabetes mellitus. Participants will receive either exercise training, cognitive training, combined training, or usual care over 20 week, followed by a 12\~24 month follow-up. Findings will inform integrated health management strategies for older adults with multimorbidity.

Eligibility

Sex

ALL

Min age

60 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Aged ≥60 years * The doctor diagnosed it as a stroke and it is in a stable stage (the diagnosis time is not limited) * Patients with concurrent hypertension and/or diabetes may also have other diseases at the same time * Be able to participate in a community intervention lasting for six months * Be informed and agree to participate in the research Exclusion Criteria: * With the aid of a walking aid (not a wheelchair), it is also impossible to walk independently to the community service center. * Lack basic communication skills and do not recognize Arabic numerals * Suffering from life-threatening diseases, with a survival expectation of less than 6 months, etc.

Primary outcome measure(s)

Intrinsic Capacity (World Health Organization Integrated Care for Older People) — 20 weeks
Assessment of intrinsic capacity using the World Health Organization Integrated Care for Older People (WHO ICOPE) framework.

Trial sites (1)

Facility	City	Region	Status
Duke Kunshan University	Suzhou	Jiangsu

More Duke Kunshan University trials in China

Comparing Acupuncture With Medication to Reduce Depression, Anxiety and Comorbid Sleep Disorders in China Recruiting

CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity Starting soon

Other trials for the same condition

Study on the Incremental Predictive Value of Early Resting-State EEG Phenotypes for Functional Prognosis and Risk Stratification in Acute Ischemic Stroke Starting soon

Study on the Correlation Mechanism and Application of Genetic Susceptibility, Hemoglobin Adaptation Changes, and Extubation Success Rate in Stroke Patients With Tracheotomy at Different Altitudes Recruiting

Art Therapy and Its Effect on Motor Function Rehabilitation in the Subacute Phase of Stroke Recovery Recruiting

Validation of the Accuracy of a Novel POCT Dry Electrolyte Analysis System in the Acute Care Setting Recruiting

SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06975501 on ClinicalTrials.gov ↗ ← All trials in China